Thursday, July 30, 2015

Vitamins: Water soluble-4: Sources, Functions, Deficiency etc

WATER SOLUBLE VITAMINS

VITAMINS B9 & B12




Vitamins
Vitamin B9
Vitamin B12
Other names
Folic acid, folacin, vitamin M, Fermentation residue factor, anti-anaemic factor
Cyanocobalamin, extrinsic factor of Castle or Animal Protein factor (APF)
Discovered by
Day et al
Ricker
Daily requirement
0.4 mg
1mg for adults
2-3 mg for children
Sources
Yeast, leafy vegetables, liver
Synthesized by colon bacteria
Liver, red meat, milk, eggs (vegetables foods are generally without B12)
Functions
Co-enzyme for the synthesis of proteins which are essential for formation and maturation of RBCs.
Promotes synthesis of thymidilic acid and DNA.
Formation and maturation of RBCs.
Formation of myelin sheath.
Deficiency
Macrocytic (megaloblastic) anaemia.
Sprue (mouth ulceration in man).
Pernicious anaemia.
Degeneration of spinal cord leading to ataxia and paralysis.

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